Description: Histopathology. The pale keratinocytes will take up a PAS stain showing glycogen in the cells.Pale cells in an acanthotic epidermis can also be seen in clonal seborrhoeic keratoses and some warts. Other epidermal changes include mild spongiosis, exocytosis of neutrophils into the epidermis which may rarely form intraepidermal microabscesses.

History: Images courtesy of Dr Alan Cameron This lesion arose slowly over a 16 week period. There was no bleeding.
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