Description: Histology nodule sebaceous carcinoma

History:

 Elderly male with no past history of melanoma developed these two lesions over a year or so. The lentigo maligna was easy to diagnose on the clinical and dermatoscopy but the nodule was more difficult. Was it an amelanotic melanoma, BCC or SCC were the initial thoughts. Histology showed a well differentiated sebaceous carcinoma. The two lesions were excised in the same specimen with 5 mm margins. Studies failed to show the mutation for the Muir Torre syndrome which can be seen with sebaceous carcinoma.

See Lentigo maligna in Dermoscopy Made Simple

EyeWiki on Sebaceous Carcinoma