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Image Number #2496 (Lentigo Maligna)

Site: Cheek

Diagnosis: Lentigo Maligna

Sex: F

Age: 79

Type: Dermlite Non Polarised

Submitted By: Wynn Hlaing

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Description: Clinical- Macule with different shades of brown colour.Dermal naevus on the lateral wall of the nose is also seen here.

History:

She has had longstanding pigmented lesion on her right malar area for more than five years which has been slowly increasing in size and darkening in pigmentation.Her skin phototype is I-II.She has no relevant history of skin cancer.

Histopathology:    Areas at least amounting to LENTIGO MELANOMA,CLARK LEVEL I,but with possible focal early LEVEL II,and features of patchy regression.

Schiffner R et al.described the "Progression model of lentigo maligna" and Stolz W also described the four characteristic features of lentigo maligna :

Asymmetric pigmented follicular openings,multiple gray dots and globules,dark rhomboidal structures and homogenous brown to dark areas occluding the follicular opening with an irregular outline.

APFOs forming an annular-granular pattern (Cognetta sign) is quite common in lentigo maligna but rare in pigmented actinic keratosis and lentigo senilis(flat seborrheic keratosis).

DermNetNZ   eMedicine   PubMed   Dermatology Online   Archives   JAAD for "Lentigo Maligna"

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